DEVELOPMENT AND EVALUATION OF A PROLONGED-RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM RESINATE
نویسندگان
چکیده
منابع مشابه
Design and Evaluation of Xanthan Gum-based Sustained Release Matrix Tablets of Diclofenac Sodium
In the present investigation, an attempt has been made to increase therapeutic efficacy, reduce frequency of administration, and improve patient compliance, by developing sustained release matrix tablets of diclofenac sodium. Sustained release matrix tablets of diclofenac sodium, were developed by using different drug: polymer ratios, such as F1 (1:0.12), F2 (1:0.16), F3 (1:0.20), F4 (1:0.24) a...
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The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...
متن کاملEvaluation of diclofenac sodium release from matrix pellets compressed into MUPS tablets.
The purpose of the study was to screen the effects of formulation factors on the in vitro release profile of diclofenac sodium from matrix pellets compressed into multiple unit pellet system (MUPS) tablets using design of experiment (DOE). Extended release of diclofenac sodium was accomplished using Carbopol 71G as matrix substance. According to Fractional Factorial Design FFD 2(3-1) four formu...
متن کاملFormulation, In Vitro Evaluation and Comparison of Sustained Release Matrix Tablets of Diclofenac Sodium using Okra Gum as Release Modifier
In the present investigation, an attempt was made to formulate sustained release matrix tablets of Diclofenac sodium using Gum acacia and Okra gum as release modifier. Six batches of sustained release matrix tablets of Diclofenac sodium were prepared by using different drug: polymer ratios viz. 1:1, 1:1.5, 1:2, 1:2.5, 1:3, and 1:3.5 for both gum acacia and Okra gum. The tablets were analyzed fo...
متن کاملFormulation, Evaluation and Comparison of Sustained Release Matrix Tablets of Diclofenac Sodium Using Tamarind Gum as Release Modifier
Background and purpose of study: In the present investigation, an attempt was made to increase therapeutic effectiveness, reduce dose frequency and improvement in patient compliance, by developing sustained release matrix tablets of Diclofenac sodium using tamarind gum as release modifier. Methods: Six batches of sustained release matrix tablets of Diclofenac sodium were prepared by using diffe...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences. Assiut
سال: 1998
ISSN: 1110-0052
DOI: 10.21608/bfsa.1998.67983